PRASASTI BANU RARA II
نویسندگان
چکیده
منابع مشابه
Acute promyelocytic leukemia cases with nonreciprocal PML/RARa or RARa/PML fusion genes.
Tumor-associated chromosome translocations usually lead to the formation of two reciprocal fusion genes: one thought to be involved in the transformation process, the other the mechanical consequence of the translocation event. In the case of acute promyelocytic leukemia (APL) blasts, the 15;17 chromosome translocation generates the putatively transforming PML/RARa fusion gene and its reciproca...
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Because PML-RARA-induced acute promyelocytic leukemia (APL) is a morphologically differentiated leukemia, many groups have speculated about whether its leukemic cell of origin is a committed myeloid precursor (e.g. a promyelocyte) versus an hematopoietic stem/progenitor cell (HSPC). We originally targeted PML-RARA expression with CTSG regulatory elements, based on the early observation that thi...
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ژورنال
عنوان ژورنال: Berkala Arkeologi
سال: 1988
ISSN: 2548-7132,0216-1419
DOI: 10.30883/jba.v9i1.496